Title: Santiago Island Vacation Packages 2026 from $537 | Expedia.com

[Santiago Island Travel Guide](https://expedia.com/Santiago-Island.dx6336381)[Hotels in Santiago Island](https://expedia.com/Santiago-Island-Hotels.d6336381.Travel-Guide-Hotels)[Vacation Rentals in Santiago Island](https://expedia.com/Santiago-Island-Vacation-Rentals.d6336381.Travel-Guide-VacationRentals)[Flights to Santiago Island](https://expedia.com/Cheap-Flights-To-Santiago-Island.d6336381.Travel-Guide-Flights)[Car Rentals in Santiago Island](https://expedia.com/Car-Rentals-In-Santiago-Island.d6336381.Car-Rental-Guide)

![](https://images.trvl-media.com/place/6336382/a64f32d4-e200-431c-89af-7a17c4de4f0e.jpg?impolicy=fcrop&w=1200&h=300&q=medium)

# Santiago Island Vacations from $537

## Book a Hotel + Flight or Car together to unlock savings

Photo by Sarah Mack

## The Latest Santiago Island vacation packages

Price found within the past 48 hours. Click for updated prices.

![Galapagos Native](https://images.trvl-media.com/lodging/10000000/9610000/9600500/9600457/68450508_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Galapagos Native

$537

per person

Apr 24 - Apr 27

found 4 hours ago

Roundtrip flight included

Guayaquil (GYE) to Isla Baltra (GPS)

7.8/10 Good! (93 reviews)

Confortablenstop over for a family

Reviewed on Dec 28, 2024

![La Casa de Marita](https://images.trvl-media.com/lodging/5000000/4230000/4224700/4224651/48faff52_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### La Casa de Marita

Save 100% on your flight

$920

per person

Mar 25 - Mar 31

found 1 day ago

Roundtrip flight included

Guayaquil (GYE) to Isla Baltra (GPS)

9/10 Wonderful! (98 reviews)

We had a lovely night stay here. You’re on an island so some ants and bugs can be expected. This isn’t The Four Seasons so if you were looking for that you would be disappointed. What you will find staff willing to go above and beyond like Jonathan, who made our stay lovely. Love that you could just walk to the beach right behind the property. The peace and tranquillity you will find here is unmatched. I think this is the best place to stay on the island. We will definitely be returning.

Reviewed on May 14, 2025

![Hotel Albemarle Galapagos Beachfront](https://images.trvl-media.com/lodging/2000000/1960000/1957300/1957249/f47b4fa8_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Hotel Albemarle Galapagos Beachfront

$873

per person

May 13 - May 19

found 18 hours ago

Roundtrip non-stop flight included

New York (NYC) to Isla Baltra (GPS)

9/10 Wonderful! (91 reviews)

The staff were wonderful and did everything possible to make sure our visit was perfect.

Reviewed on Jan 8, 2026

![Royal Palm Galapagos, Curio Collection Hotel by Hilton](https://images.trvl-media.com/lodging/13000000/12540000/12535100/12535025/215f955b_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Royal Palm Galapagos, Curio Collection Hotel by Hilton

$1,099

per person

Apr 24 - Apr 27

found 3 hours ago

Roundtrip flight included

Guayaquil (GYE) to Isla Baltra (GPS)

9.2/10 Wonderful! (52 reviews)

We had the best time ever! We will definitely be back! The place is beautiful!

Reviewed on Feb 19, 2026

![Natura Gardens Galápagos Hotel](https://images.trvl-media.com/lodging/93000000/92140000/92133100/92133071/43e7a815_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Natura Gardens Galápagos Hotel

$563

per person

Apr 24 - Apr 27

found 4 hours ago

Roundtrip flight included

Guayaquil (GYE) to Isla Baltra (GPS)

7.6/10 Good! (4 reviews)

One of three days water in entire building was shut off. Had to wait for several hours for water to return. Though Owner and family are very nice people

Reviewed on Sep 22, 2025

Don't see what you're looking for?

See all available trips from Columbus to Santiago Island

[View all trips](https://expedia.com/go/package/search/FlightHotel/2026-03-19/2026-03-26/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=GPS&NumRoom=1&NumAdult=2&NumChild=0&paandie=true)

![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh)

## 

The Annual Vacation Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.

[Book now](https://expedia.com/deals?rfrr=PKG_SPRING_PROMO_6336381)

## Santiago Island Hotel Deals

![Hostal cielo azul](https://images.trvl-media.com/lodging/91000000/90840000/90837600/90837535/67514c1e_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Hostal cielo azul

Puerto Villamil Pedregal 1 Bella Vista Islas Galápagos

I traveled from Florida to Galapagos Island wirh my family, but they have a issue and Quito aereopuerto, that cause to me traveled by myself, but Im arrived to Isabella Island alone , the owner pick up me from muelle, and help me with everything, phone calls to call my family, safety place, thank ...

Reviewed on Jul 27, 2023

[Get rates](https://expedia.com/Hotel-Search?startDate=3%2F5%2F2026&endDate=3%2F6%2F2026&selected=90837535&PinnedHotelID=90837535&HadPinnedHotel=true&regionId=6336381)

[](https://expedia.com/Hotel-Search?startDate=3%2F5%2F2026&endDate=3%2F6%2F2026&selected=90837535&PinnedHotelID=90837535&HadPinnedHotel=true&regionId=6336381)

[See all properties in Santiago Island](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=2%2F20%2F2026&endDate=2%2F21%2F2026&regionId=6336381)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Find the Best Santiago Island Vacation Packages

## Santiago Island Essential Information

| Language        | Spanish               |
| --------------- | --------------------- |
| Currency        | U.S dollars           |
| Local Welcome   | ¡Hola!                |
| Local Goodbye   | Adiós                 |
| Closest Airport | Seymour Airport (GPS) |

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\* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.